How can I protect against oxalates? | Masterjohn Q&A Files #324

Question: How can I protect against oxalates? Short Answer: Getting 300-400 mg calcium between food and supplements at each meal will minimize oxalate absorption. Maintaining postprandial urine pH in the 6.4-6.8 range by getting 3-5 grams of potassium per day from food or from organic acid salts such as potassium citrate will prevent its crystallization in the …

Why Should Postprandial Glucose Be Kept Under 140 mg/dL? | Masterjohn Q&A Files #323

Question: Why should postprandial blood glucose be kept under 140 milligrams per deciliter? Short Answer: When blood glucose rises above 140 mg/dL, this is the approximate point at which it spills into the polyol pathway at a greater-than-normal rate, which represents a suboptimal state of metabolism that is likely to hurt antioxidant status and compromise detoxification pathways …

What is the relationship between copper and estrogen? | Masterjohn Q&A Files #322

Question: What is the relationship between copper and estrogen? Short Answer: Estrogen moves copper from the mother’s bloodstream to the fetus during pregnancy. Its action at the intestines is poorly understood but I believe estrogen and progesterone interact to promote intestinal copper absorption. Maintaining pregnancy-level hormones while not pregnant poses a risk of promoting too much absorption …

How to slow or reverse graying of hair? | Masterjohn Q&A Files #321

Question: How to slow greying of hairs and potentially reverse it? Short Answer: What works for any given individual will likely be to find the weakest link and fix it, from among the following systems: the signaling of energy abundance (body fat, insulin sensitivity, thyroid hormone, adequate protein, individualized meeting of carbohydrate needs, good management of psychosocial …

How Much Iron Can We Absorb At Once? | Masterjohn Q&A Files #320

Question: How much iron can we absorb at once? Short Answer: High-dose iron will produce more total absorbed iron, but will also leave more in the gut, which could cause constipation or disturb the gut microbiome. If desperate for quick relief, 200 milligrams per day of iron taken in the morning will work faster than lower doses …

What cofactors are needed to synthesize and recycle BH4? | Masterjohn Q&A Files #319

Question: What cofactors are needed to synthesize and recycle BH4? Short Answer: Zinc, magnesium, potassium, and niacin are the cofactors needed for the synthesis and recycling of BH4. Folate and methylation are not involved, though high-dose folate or folic acid could hypothetically hurt BH4 recycling since both are recycled by dihydrofolate reductase (DHFR).