Short answer: Low or low-normal alkaline phosphatase may raise the plasma B6 level over the cellular level. Tryptophan metabolites in urine reflect the B6 requirement for the kynurenine pathway, and this requirement increases with more estrogen, more inflammation, or a higher protein intake. This episode was cut from the original Q&A session that you can find here. …

Short answer: 4-6 hours after a meal the small intestine is emptied and the insulin-to-glucagon ratio declines; 25 hours after, hepatic glycogen is emptied; 5 days later the brain is adapted to ketones and gluconeogenesis reaches its minimal level. Moving from one to the other cannot occur with a small piece of signaling like the bite …

Short answer: Probably not. Animal studies showing a difference use huge doses in an unrealistic context. Human studies show they don’t at doses used. Human effect on PSA is vulnerable to regression to the mean and thoroughly unconvincing. This episode was cut from the original Q&A session that you can find here. DISCLAIMER: I have a PhD …

Short answer: Trust the CGM. HbA1c is confounded by red blood cell turnover and fructosamine 3-kinase activity. This episode was cut from the original Q&A session that you can find here. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing …