How to lower Sex Hormone-Binding Globulin (SHBG)? | Masterjohn Q&A Files #103

Question: How to lower Sex Hormone-Binding Globulin (SHBG)?  Carrie: SHBG is like bane of my existence. I have no idea how to get SBHG down once it’s up. Boy, I actually talk to practitioners about this all the time to figure that out. I would agree that supplements that for SHBG, it’s very hit or …

Can Cats and Dogs Get COVID-19? An Emerging Controversy

Whether pets such as cats and dogs can get COVID-19 is a subject of emerging controversy. Just today, a preprint* originally released on March 31 suggesting pets can be infected was published in Science. On the other hand, a new preprint was released today suggesting domestic pets under typical domestic circumstances are not being infected. …

Why does estrogen regulate tryptophan metabolism? | Masterjohn Q&A Files #102

Question: Why does estrogen regulate tryptophan metabolism? Chris: I think that it’s basically the body trying to make sure that the baby has enough niacin because chronic estrogen exposure would occur during pregnancy. When I was doing my niacin research, one thing that I found is that women seem to need more total niacin than …

The Coronavirus May Circulate in a Community For 4-6 Weeks Before Detection

Two days ago, Seattle-based public health researchers released a new study as a preprint* suggesting that COVID-19 cases spread throughout communities within Washington state for 4-6 weeks before the first community-acquired case had been identified. This is deeply concerning, because it suggests that by the time the first case is identified in a community it …

Insomnia is different between people who are and aren’t on HRT? | Masterjohn Q&A Files #101

Question: Insomnia is different between people who are and aren’t on HRT? Carrie: Yes, sort of. If it’s strictly a hormone issue, if she says, “I’ve never had insomnia. I turned 45 and I got insomnia. And, oh, by the way, I’m also having irregular periods and hot flashes and night sweats and all this …