Methylglyoxal regulates glycolysis in a way that prevents dangerous accumulation of glyceraldehyde, and that conserves glucose during carbohydrate restriction. Its rise on a low-carb Atkins diet makes physiological sense because it conserves glucose and even allows gluconeogenesis from fatty acids. Nevertheless, high methylglyoxal levels causally contribute to diabetes, and this seems to be a stress response that should not be chronically elevated.

Mastering Nutrition Episode 13: Wait a Second, Is Glycation Actually GOOD For You?

  In this episode, I wrap up glycation week by discussing why glycation may play essential physiological roles in the body. In the early days of methylglyoxal research, Albert Szent-Gyorgyi, who won the 1937 Nobel prize in Physiology or Medicine for his discovery of vitamin C and critical steps in energy metabolism, saw the molecule …

Weighing in on the Fermented Cod Liver Oil (FCLO) Controversy

Many people have been asking me to weigh in on the controversy that is erupted this week with the publication of Dr. Kaayla Daniel’s report arguing that fermented cod liver oil (FCLO) produced by Green Pasture is rancid, low in fat-soluble vitamins, made from pollock rather than cod, and adulterated with trans fat-containing vegetable oil. …

How to Cook Liver and Make it Taste Not-Bad

Liver is an absolute nutritional powerhouse, nature’s multivitamin. Many people have bad experiences with liver because they don’t like the taste, but these negative experiences can be minimized by starting with high-quality, fresh liver, and then storing, preparing, and cooking it right. Tip 1: Grass-Fed Liver First off, start with grass-fed liver. It’s likely to …

Wheat Belly — The Toll of Hubris on Human Health

Dr. William Davis, Milwaukee-based “preventive cardiologist” and Medical Director of the Track Your Plaque program, argues in his new book, Wheat Belly: Lose the Wheat, Lose the Weight, and Find Your Path Back to Health, that “somewhere along the way during wheat’s history, perhaps five thousand years ago but more likely fifty years ago, wheat …