Wheat Belly — The Toll of Hubris on Human Health

Dr. William Davis, Milwaukee-based “preventive cardiologist” and Medical Director of the Track Your Plaque program, argues in his new book, Wheat Belly: Lose the Wheat, Lose the Weight, and Find Your Path Back to Health, that “somewhere along the way during wheat’s history, perhaps five thousand years ago but more likely fifty years ago, wheat …

Where Do Most AGEs Come From? O Glycation, How Thy Name Hast Deceived Me!

I’ve written a few posts about advanced glycation endproducts (AGEs) in the past, which can be found here.  These posts include a refutation of the common belief that the “receptor for AGEs” (RAGE) is actually a receptor for AGEs, and a refutation of the implausible and unreliable data suggesting that butter is a major source …

Genes, LDL-Cholesterol Levels, and the Central Role of LDL Receptor Activity In Heart Disease

Are high concentrations of LDL-cholesterol a major cause of heart disease?  If we are a proponent of the “lipid hypothesis,” we say yes.  If we are a “cholesterol skeptic,” we say no — total cholesterol, LDL-cholesterol, LDL particles, triglycerides, and other blood lipids have little or nothing to do with heart disease. I believe both of these positions …

Eating Fat and Diabetes — Response to Bix Weber

Melissa McEwen recently brought to my attention a blog post by Bix Weber, the Fanatic Cook, “Diabetes is a Disorder of Fat Metabolism.” Weber cites a 2009 study published in The Journal of Clinical Investigation entitled “Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans” …

What Can Modern Toxicology Tell Us About Food Toxins and Food Intolerances?

“The dose makes the poison.” — Paracelsus (1493-1541) “What is food to one is bitter poison to others.” — Lucretius (ca. 99 BC — ca. 55 BC) This post will be the first in a series of posts on food toxins and food intolerances.  As an introduction, I’d like to review some of the recent …