So far we’ve seen that glycine or collagen supplements can improve sleep, tendon health, and blood sugar. But many of you have asked me, should we be concerned that they can raise oxalate levels? This could potentially increase the risk of kidney stones.

There’s about a ten percent chance you could be at risk of a kidney stone some day, and if you’re in that minority you should be concerned about your exposure to oxalates. Glycine is very unlikely to generate oxalates, but collagen may, especially if you are deficient in vitamin B6. In this video, I describe how to figure out if this is relevant to you and what to do about it.

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3 Comments

  1. I deal with painful vulvodynia; but I also have osteopenia and degenerated disc problems;
    I’ve been reading how collagenpeotides can help with the bones,but will it flare up my vuvlodynia due to oxylates?

  2. Hi Chris: My name is Kay and I have been reading your article, very interesting. In late 2016 I had the horrible experience of having a kidney stone attack and was in the hospital for three days trying to pass the stones and when I did I passed several of them the size of bebe’s, it was so painful that I would rather give birth to six babies all at once and now almost two years later my kidney still hurts and when I think that I might be trying to pass more my Doctor has prescribed a medication to help dialate the uter tube. I have two very bad knees caused from injuries, walking with a walker and thought that Collagen might help strengthen my knees some, but sounds like maybe I should rethink that. Thank you much for your information.

  3. Hi Chris, could it not be the case that oxalates are actually a much wider problem – but kidney stones get singled out because of the acute pain and relative ease to analyse the problem? Mercury or zinc oxalate, for example, are highly insoluble, so even though they may have the potential to accumulate and cause problems maybe we don’t see them so much in the urine or blood. Considering that gut flora imbalance and especially fat malabsorption are so common and increase oxalate absorption massively, I wouldn’t be surprised. I remember Dr Shaw saying that he believes that endothelial oxalates could turn out to be a big risk factor in heart disease. Think it’s also worth mentioning that citrate is vital. Where I am traditionally lemon juice is added to vegetables and tea. Maybe that’s the reason why milk found its way into English tea – so the calcium could reduce oxalate uptake?!

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