Introducing Chris Masterjohn Lite

Here are 3 ways to clear stubborn inflammation: managing your fatty acids, taking a new supplement that jump-starts the resolution process, or going with the aspirin protocol from a few episodes ago. Tune in for the details!

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Here are links mentioned in this episode:

The last episode on omega-6 and omega-3 fatty acids:

The aspirin episode:

Here are products mentioned in this episode. Purchasing them using these links earns me a small commission at no extra cost to you, which helps support the free work I provide:

Arachidonic acid supplements:

Specialized pro-resolving mediators:

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  1. Do you believe the SPMs are something that can be taken longer term if they are beneficial, or would they only be temporary? Can long term use lead to anything negative?

  2. Hey Chris!

    Do you believe the Arachidonic Acid potential to be inflamatory can cause trouble with people who have autoimmunity/overactive immune system?

    I’m curious as to why Arachidonic Acid isn’t a praised supplement for autoimmunity because from the looks of it it certainly should be!

    Thanks so much!

    1. Yes, it isn’t a miracle cure, and if the inflammation isn’t resolved, the AA can be used to continue the inflammation. However, AA is still needed to resolve the inflammation.

      Most people are still stuck in the outdated 1990s model where AA is inflammatory and EPA is anti-inflammatory. Hardly anyone is caught up on the resolution literature.

  3. Hi Chris,
    I was wondering if you could comment on aspirin increasing the risk of bleeding. Not just gastrointestinal bleeding, but also bleeding and bruising generally due to its blood thinning effect. Will your recommendations on taking aspirin with glycine & increasing urine pH help with this? There are people who recommend taking vitamin K to counteract the blood thinning but I have not found this having much of an effect. Thank you so much for your work! Ava

    1. Hi Ava,

      They might help with that, since salicylate lowering COX activity is responsible for a portion of it. I don’t think they eliminate the bleeding risk, though, since the acetylation of COX will lower prostaglandins needed for clotting.

  4. Hi Chris,

    I’d like to try this out, but am having a hard time taking enough glycine.
    I’ve started several times and felt lousy, but after switching to collagen (as you recommended) and dosing up very slowly, I can now tolerate it (also as powder or salt) and feel better in general.
    However if I take too much, especially in the evening, I can’t get out of bed the next morning. Yesterday I took only 2 g for dinner (to balance the methylation system, as I ate 2 large eggs), knowing it could knock me out in the morning. This was already too much. I have a general issue with getting up in the morning, but this makes it really bad and also hard to reach at least 10 g of glycine a day.
    Hope you can give me a hint what my body is missing!

    Kind regards,

    1. I’m not sure, perhaps the inhibitory effect of glycine is not balanced by adequate glutamate, so you might need more protein or more carbs. But I would not go up beyond the dose that gives you benefit. In other words, don’t be ideological about the numbers. Tailor it to your own response.

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