Chris Masterjohn, Phd. talks about Nutrition in Neuroscience
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Chris Masterjohn, Phd. talks about Nutrition in Neuroscience

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Part 3 of how NUTRITION has a HUGE impact on your BRAIN!

Everything in your brain is something you ate, something you made from something you ate, or, in a few cases, something your mother ate. Nutrition impacts your mental and emotional health, the function of your five senses, and your conscious and unconscious control over your body movements.

Join me as I lead you in a safari through the textbook, “Neuroscience,” pointing out along the way all the interesting connections to nutrition. Listen in for part 2 on the THE FIVE SENSES!


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This episode is brought to you by Ample. Ample is a meal-in-a-bottle that takes a total of two minutes to prepare, consume, and clean up. It provides the right balance of nutrients needed for a single meal, all from a blend of natural ingredients. Ample is available in original, vegan, and keto versions, portioned as either 400 or 600 calories per meal. I'm an advisor to Ample, and I use it to save time when I'm working on major projects on a tight schedule. Head to https://amplemeal.com and enter the promo code “CHRIS15” at checkout for a 15% discount off your first order.”

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Nutrition in Neuroscience Show Notes

00:35 Cliff Notes

08:50 Exteroception and proprioception are mediated by mechanoreceptors.

11:32 Pain is mediated by nociceptors, which are unspecialized, low-sensitivity neurons.

13:10 Capsaicin activates the TRPV1 receptor, which is also activated by hot temperatures.

15:12 The use of topical capsaicin to relieve chronic pain

18:25 Interoception is our sense of the physiological state within the body.

20:20 Why anorexics crave spicy foods

22:17 Managing pain in the peripheral nervous system; acidity sensitizes pain receptors.

24:12 Managing the fatty acids that help resolve inflammation, particularly arachidonic acid and DHA, to help with peripheral sensitization to pain

25:59 Combining aspirin with fish oil, glycine, and bicarbonate to help with peripheral sensitization to pain

30:50 Central sensitization to pain occurs through an LTP-like process, which is mediated by NMDA receptors.

32:47 Overview of vision and the importance of vitamin A

38:21 The role of vitamin A in preventing night blindness and its very closely related role in setting your circadian rhythm

41:54 Overview of hearing

44:20 Nutrients important for hearing

45:44 Overview of smell

47:41 Overview of taste

Nutrition in Neuroscience Related Content

Chris Masterjohn Lite: How to Fix Chronic Pain

Chris Masterjohn Lite: Do you really need to be taking fish oil?

Chris Masterjohn Lite: The Omega-6 / Omega-3 Fatty Acid Ratio: Should You Care?

Chris Masterjohn Lite: Why Aspirin Goes Best With Bicarbonate and Glycine

Chris Masterjohn Lite: 3 Ways to Clear Stubborn Inflammation

Vitamin A Plays an Essential Role in Setting the Circadian Rhythm and Allowing Good Sleep, on the role of vitamin A in melanopsin function.

Mastering Nutrition Episode 10: How to Know if Your Genetics Contribute to Your Sensitivity to Blue Light and Poor Sleep, and What to Do About it on genetic variation in the melanopsin protein.

Mastering Nutrition: Why You Should Manage Your Zinc Status and How to Do It, since the opsin proteins are zinc-dependent.

Assorted other posts on zinc.

Testing Nutritional Status: The Ultimate Cheat Sheet is a comprehensive guide for testing nutritional status for all the nutrients discussed in this episode, and more. Use the code MASTERINGNUTRITION for $5 OFF.

Nutrition in Neuroscience Research

The textbook, Neuroscience.

Depletion of Plasma Glycine and Effect of Glycine by Mouth on Salicylate Metabolism During Aspirin Overdose

Diuresis or Urinary Alkalinizing for Salicylate Poisoning

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5 Comments

  1. Chris,
    I forgot to say that castor oil packs, CBD oils and ointments with snake venoms applied topically all have pain relieving effects. I use it regularly for pain in my spine, knee, etc as well as apply to soft tissues for various abdominal area pains. What is the mechanism? An essential oil Wintergreen, the real one, as most are fake, is also effective for pain. Wintergreen and birch tree oils are not related botanically at all , but both 85-99% consist of almost entirely of methyl salicylate compound. These oils have an analgesic effect which has been compared to cortisone.

  2. Super. Thank you
    Chris, a late friend of mine before being diagnosed with cancer had full body shingles. The pain was nothing short of prolonged agony.. He was incapacitated by pain to the degree of wanting to take his life. . We talked about applying capsicum but he couldn’t imagine it. You spoke about topical application of capsicum. I don’t see in what circumstances it could be done other than something like shingles.

    1. It’s used for neurological pain from herpes or diabetes, might have other applications but needs to be done with a doctor.

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