Chris Masterjohn Ask Me Anything About Nutrition February 17 2019 CMJ Masterpass

Chris Masterjohn Ask Me Anything About Nutrition February 17 2019 CMJ Masterpass

On February 17, members of the CMJ Masterpass joined me in a live Zoom meeting to ask me anything about nutrition, and here’s the full recording!

We talked about lots and lots of things: using the Oura ring to measure HRV and optimize athletic performance and recovery, what to do in the context of diabetes if T3 doesn’t increase your heat production, whether keeping warm with clothing has health benefits if you can’t get your body temperature up, what to do about high morning glucose, how to get rid of heavy metals, how to repair bone, what vegans should do to get arachidonic acid levels up, zinc and copper supplementation, kale and spinach smoothies, blood donation when your transferrin saturation is high but your ferritin is low, dealing with a high resting heart rate, lots of questions on organic acid markers, how estrogen can mess up vitamin B6 markers even in men and when that means you should lower your protein intake, whether combining carbs and fat makes people fat, how many eggs to eat a day, how the nutritional needs of children are special, vitamin A toxicity in and out of pregnancy, creatine non-responders, intermittent fasting hurting sleep…

…. and much more!

If you’d like to participate in the next Q&A, consider joining the CMJ Masterpass. Use this link to get a 10% lifetime discount:

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AMA About Nutrition Show Notes

8:24 What to do, in the context of diabetes, if T3 supplementation does not increase heat production?

17:03 If you can't get your body temperature up to normal, will wearing more clothing to keep warm improve health?

19:40 What to do about elevated morning blood glucose in the mid 90s.

21:38 What are my thoughts on detoxing heavy metals?

23:36 What nutrients are needed to break down old, damaged bone and build new, healthy bone?

28:06 What should an ethical vegan with low delta-6 desaturase activity do to bring low arachidonic acid levels up to normal?

30:20 How to manage the zinc-to-copper ratio and what to do if zinc and copper are both low-normal when supplementing with 15 mg of zinc and 1 mg of copper.

34:20 How to lower a resting heart rate in the 80s or 90s.

37:00 Is a daily green smoothie with spinach or kale a risk because of thallium, goitrogens, oxalates, or other concerns?

39:20 For someone who is homozygous for the H63D allele of the iron- and hemochromatosis-related HFE gene, if ferritin is low but transferrin saturation is high, should they still donate blood?

48:20 For someone who is taking 45 mg of vitamin B6 as P5P but has xanthurenate, kynurenate, and quinolinate high in the urine as markers of vitamin B6 deficiency, and who is a man with high estrogen, what should they do?

56:18 What to do if taking biotin and yet beta-hydroxyisovalerate is elevated.

57:17 What to do if gamma-tocopherol levels are low-normal while taking 100 IU/d of alpha-tocopherol.

59:30 Does mixing carbohydrate with fat cause people to get fat because of the Randle cycle? (continued at 1:21:00)

1:03:35 Do children need less nutrients than adults because they have lower body weights, or do they need more nutrients than adults because they are growing faster? (

1:07:12 What to do for a five-year-old who is unusually exhausted, and how to assess their nutritional needs. (Brief followup at 1:35:50)

1:09:30 Concerns about vitamin A intake during pregnancy.

1:12:24 How to use an Oura ring to monitor HRV and optimize recovery and performance.

1:15:40 What are “parent essential oils”? Should we get these instead of cold-water fish oils? Response to Brian Peskin’s theory.

1:21:00 More on whether the combination of carbs and fat makes people fat as a result of the Randle cycle.

1:29:00 Matt stone and the “overdeification” of vitamin A. Or, are there many people who are vitamin A deficient? Hypersensitivity reactions, fatty liver, overzealous use of cod liver oil, and other concerns.

1:35:50 How to deal with the fact that blood tests for nutritional status aren't adapted to children.

1:37:05 How much fatty fish to eat.

1:38:05 Nutritional strategies for glucose 6-phosphate dehydrogenase (G6PDH) deficiency.

1:42:58 If berberine lowers LDL-C and total-to-LDL-C but raises ApoB, what does this mean?

1:45:50 How to interpret the pattern of high citrate, low cis-aconitate, low glutamate, and high glutamine. (Followup at 1:53:05)

1:47:20 What do I think about Loren Cordain, his views on salt and dairy, and his opinion of Chris Kresser?

1:53:55 What to do about acne that gets worse with stress and better with cardio?

1:55:37 For MTHFD1, PEMT and MTHFR, should I be supplementing choline?

1:56:13 How to bring up low levels of arachidonic acid.

1:57:17 Using blood tests to determine whether you should increase your calcium intake.

1:57:45 Alex Leaf answers a question about creatine non-responders and methylation.

1:59:22 Could neurotransmitter levels be artificially low on the Genova ION panel if you fasted for 24 hours before having samples taken?

2:00:07 When to take tryptophan on a ketogenic diet.

2:00:52 When should you take creatine, if you don't have an MTHFR SNP?

2:01:30 My thoughts on PQQ and CoQ10 supplements.

2:02:02 What to do when high selenium levels won't come down, even if you've stopped supplementing.

2:02:24 Is four eggs a day too much?

2:03:05 Are low total omega-6 levels on the ION panel a cause for concern?

2:03:50 What to do about high arsenic.

2:04:24 What to do about fungal infection suggested by elevated D-arabinitol.

2:05:33 Migraines and twitching caused by coffee that responds to electrolytes.

2:09:55 What to do if signs and symptoms of zinc deficiency persist despite taking 75 mg zinc gluconate per day.

2:11:35 What to do if intermittent fasting beginning before 3:00 PM hurts sleep.

2:13:55 What to do about high-normal TSH and no diagnosis of a thyroid disease.

Links Mentioned in the AMA

Copper-Rich Foods

Stephan Guyenet and Chris Masterjohn Talk About “The Hungry Brain”

Alex Leaf on Why You May Reconsider Buttering Your Potato

Vitamins for Fetal Development: From Conception to Birth

My Recommendations for Sleep


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  1. Would you please help to understand this?
    Calcium normal 9.2 but PTH is 96 H (range in test shows 14-64pg/ml)

    1. Hi Chris I hope you can respond to my comment
      Would you please help to understand this?
      Calcium normal 9.2 but PTH is 96 H (range in test shows 14-64pg/ml)

    2. HiZeynab, I just want you to know Chris is super busy finishing his Vitamins&Minerals 101 book. If you post your question on social media, there is a more likely chance for a reply at this time. Thank you. Support staff at

  2. Besides the hunger/palatability effect that you mention, there is a big difference — depending on the numbers of mixed diet. Insulin is not the while picture but still the major player and the first order idea that carbohydrate directly and through insulin and other hormones directs the disposition of fat. Isn’t this biochem 101? You can see it in a test tube.
    In addition, there seems to be misunderstanding of the Randle cycle. As we learn it, it responds to fat by feeding back on carbohydrate metabolism but you have to be careful to avoid the pin-ball machine view of metabolism — this happens and then this happens. The Randle cycle is part of the whole feedback loops that prevents things from changing. You have to break through that by going very low carb or low fat to see any changes. Does that make sense?

  3. I missed this But I just noticed a post you did on protein before bed. Wondering if you could ever address eating fat before bed after attending a Poliquin course he mentioned that high Fat before bed reduce the ability of growth for Mont to do it’s job during the sleep phase.

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