Why does methylfolate act as the off-switch for the glycine buffer system? | Masterjohn Q&A Files #272

Short Answer: When we have too many methyl groups, MTHFR is shut off and methylfolate is not produced. Therefore, methylfolate acts as a signal that we do not have enough methyl groups, and shuts off the glycine buffer system, which is only active when we have too many methyl groups. 

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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

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