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Is it safe to take creatine when nursing? | Masterjohn Q&A Files #81

Question: Is it safe to take creatine when nursing? If you felt fatigued and you took the creatine and all of a sudden that started reversing, then you either felt fatigued because you had low creatine synthesis, or you felt fatigued because you had a methylation problem. Those aren’t mutually exclusive. If you’re not methylating …

Can you explain plant polyphenols and hormesis? | Masterjohn Q&A Files #80

Question: Can you explain plant polyphenols and hormesis? In brief, our detoxification system didn’t evolve to handle the toxins of modern society. Modern society invents a new chemical. Our body knows it’s a toxin, but it doesn’t know it because we were exposed to it for millions of years. It knows it because it has …

What to do when serum magnesium is high but RBC magnesium is low? | Masterjohn Q&A Files #79

Question: What to do when serum magnesium is high but RBC magnesium is low? The magnesium in the blood and the hair is high. When you say blood, I’m assuming this is serum or plasma because the RBC magnesium is low. I’m hoping that’s not whole blood magnesium in which case it would be hard …

Is there a potential for adverse effects of 5-10 mg of folate for heterozygous MTHFR? | Masterjohn Q&A Files #78

Question: Is there a potential for adverse effects of 5-10 mg of folate for heterozygous MTHFR? Is there a potential? Yeah. The tolerable upper intake level for folate was set at 1 milligram on the basis that there are rare hypersensitivity syndromes that have caused reactions to 1 milligram or higher. On the basis that …

Is folate unstable in frozen liver or just in frozen veggies? | Masterjohn Q&A Files #77

Question: Is folate unstable in frozen liver or just in frozen veggies The answer is folate is stable in frozen liver. It is not stable in frozen greens.  This Q&A can also be found as part of a much longer episode, here: https://chrismasterjohnphd.com/podcast/2019/03/30/ask-anything-nutrition-march-4-2019 If you would like to be part of the next live Ask …

How much vitamin C should I take with collagen? | Masterjohn Q&A Files #76

Question: How much vitamin C should I take with collagen? There’s no evidence that you need to take vitamin C with collagen. There is a study by Keith Baar, who showed that 15 grams of gelatin, not collagen, but I suspect the collagen is exactly the same, 15 grams of gelatin but not 5 grams, …

Should I take 3 grams of leucine per meal? | Masterjohn Q&A Files #74

Question: Should I take 3 grams of leucine per meal? Leucine is metabolized into a leucine metabolite that is the signal of protein synthesis. It’s the thing that tells your muscles whether they should be synthesizing protein. But do you synthesize more protein when you upregulate all the factors of muscle protein synthesis? Well, that …

What are your thoughts on root canals? | Masterjohn Q&A Files #73

Question: What are your thoughts on root canals? Before Weston Price embarked on his journeys that led to the publication of Nutrition and Physical Degeneration, which is an epic pioneering work in nutritional anthropology, before he did that, he spent 25 years as the first research director for what became the American Dental Association, researching …

What does it mean when histamine intolerance and blood sugar dysregulation occur together? | Masterjohn Q&A Files #72

Question: What does it mean when histamine intolerance and blood sugar dysregulation occur together? Well, if his blood sugar is no longer as stable and he has histamine intolerance, then that drug probably interferes with vitamin B6 metabolism. Let me try to take one minute to see if I can find quick information on this. …