Showing: 21 - 30 of 331 Articles

Brain Fog on Calcium, Vitamin D, or K2 | Masterjohn Q&A Files #310

Question: Why would vitamin D, vitamin K2, and calcium give me brain fog? Short Answer: Most likely by decreasing serum phosphorus. The solution is to balance these nutrients with vitamin A and phosphorus. This episode was cut from the original Q&A session that you can find here. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise …

Why Plasma Zinc is the Best Marker of Zinc Status | Masterjohn Q&A Files #309

Short Answer: Plasma zinc is the single most important marker of zinc status. Urine zinc may decline faster in deficiency. Hair zinc increases with supplementation but does not decrease in deficiency. Plasma zinc is decreased by inflammation, oxidative stress, the ovulatory and luteal phases of the menstrual cycle, probably pregnancy and oral contraceptive use, and …

Glutathione Intolerance: Getting to the Bottom of It | Masterjohn Q&A Files #308

Question: Why do many chronically ill people have an intolerance to glutathione, and what can be done at home to determine the cause? Short Answer: It could be byproducts of any of the three amino acids that make up the glutathione molecule, which include the individual amino acids, ammonia, hydrogen sulfide, sulfite, and propionyl CoA, …

Statins Vs. Sulfur for Heart Disease | Masterjohn Q&A Files #307

Short Answer: From the trials, statins seem to reduce heart disease risk and total mortality, but it is impossible to separate this from conflicts of interest and industry funding. There are plausible mechanisms by which they may hurt mitochondrial function and promote soft tissue calcification. Dietary sulfur appears to lower cholesterol. While Lester Morrison showed 1500 …

Why would someone not tolerate methyl donors even if they need them? | Masterjohn Q&A Files #306

Short Answer: I believe most methyl donor intolerances are a result of deficiencies in the glycine buffer system, which requires glycine, vitamin A, fasting (glucagon), androgens, riboflavin, unmethylated folate (THF), and iron. No one should expect to tolerate 30 milligrams of folate, however, and there is almost never a reason to use doses that high.

Does whey protein hurt the kidneys or otherwise hurt our health? | Masterjohn Q&A Files #305

Question: Does whey protein hurt the kidneys or otherwise hurt our health? Short Answer: The main problem with too much protein, particularly animal protein, is that acidity may hurt the bones and increase the risk of calcium oxalate kidney stones, but this can be obviated by balancing it with organic acids, which have bicarbonate-sparing effects that are …

Does glucose handling in the brain decline with age? And if so, does this serve as a rationale to supplement with MCT oil to prevent cognitive decline? | Masterjohn Q&A Files #304

Does glucose handling in the brain decline with age? And if so, does this serve as a rationale to supplement with MCT oil to prevent cognitive decline? Short Answer: Energy metabolism in general declines across the body with aging, but energy metabolism seems to stay healthy enough in the brain in people who do not …

How to Increase or Decrease SHBG? | Masterjohn Q&A Files #302

Short Answer: SHBG is increased by adiponectin (vitamin K2, insulin sensitivity), thyroid hormone, fasting physiology (AMPK, fat oxidation), and estrogen (especially estrone), while it is decreased by insulin resistance, obesity, the fed state and carbohydrate-dominant physiology, androgens, and polyunsaturated fat. This episode was cut from the original Q&A session that you can find here. DISCLAIMER: I have …

Protein and Longevity | Masterjohn Q&A Files #301

Short Answer: While protein restriction may have value in people with established cancer or kidney disease, cycling robustly between fasting and feeding states is likely to provide all the value that restriction of protein or calories might otherwise provide, and a high protein intake supports bone mass, muscle mass, and the detoxification of carcinogens, all …