Question: I just saw an email from Matt Stone referring to the overly deified nutrient vitamin A. Also, a few Weston A. Price Foundation bloggers are starting to spread the word about being sick on a high vitamin A diet. Any thoughts about this and comments about Vitamin A being toxic? You shouldn’t deify …
Question: Is it ok to mix carbs and fat? There are a lot of people on the internet that claim the Randle cycle is behind America being fat, since the standard American diet is mixed in fats and carbs. Yet, I feel great on a diet of about 30% protein, 30% fat, and 40% carbs, …
Question: Can you explain what parent essential oils are? I was given some articles that seemed to be saying that high-dose cold-water fish oils are damaging to cell membranes and mitochondrial function. “Parent essential oil” is a term invented by Brian Peskin, who looked at some data that said it’s not clear that supplementing with …
Question: What are your thoughts on monitoring HRV for optimizing performance? Measure your HRV every night and you stop exercising entirely to get a baseline. You completely stop working out, you don’t go “oh no I’m going to lose my muscle mass,” nothing’s going to happen for a week or two. And this is the …
Question: Why did the FDA have a vitamin A requirement during pregnancy at 8,000 IU, which is much higher than the IOM recommendations in the past? I have no idea. I do know that the concerns around vitamin A during pregnancy are that in the first weeks of pregnancy, 10,000 IU and higher has been …
Question: Does mixing carbohydrate with fat cause people to get fat because of the Randle cycle There’s a theory floating around on the internet that mixed diets are more fattening than low-carb or low-fat diets because of the metabolic competition between glucose and fatty acids. I don’t believe this to be true because, in the …
Question: What to do if gamma-tocopherol levels are low-normal while taking 100 IU/d of alpha-tocopherol. My initial impression is that there is nothing wrong because I don’t care that much about gamma tocopherol. My doctoral research specialized in gamma tocopherol and there is some evidence that gamma tocopherol does some things that alpha tocopherol doesn’t …
Question: What to do if taking biotin and yet beta-hydroxyisovalerate is elevated. Well in theory that’s a marker of biotin deficiency, but you might have a defect in a biotin-dependent enzyme so you can try 5 milligrams, but if you still have high beta hydroxy isovaleric you need to start looking at a metabolic disorder, …
Question: For someone who is taking 45 mg of vitamin B6 as P5P but has xanthurenate, kynurenate, and quinolinate high in the urine as markers of vitamin B6 deficiency, and who is a man with high estrogen, what should they do? If you have xanthurenate and kynurenate spilling into your urine, it means that quinolinate …
Question: For someone who is homozygous for the H63D allele of the iron- and hemochromatosis-related HFE gene, if ferritin is low but transferrin saturation is high, should they still donate blood? H63D is one of the genes that predisposes to hemochromatosis, a condition of iron overload. Most clinicians who work in this area do not …