Do you have trouble sleeping, or wish you felt more rested and energized during the day? Glycine might be one of the best things you can try. It doesn’t just have a calming effect, but it improves sleep quality and can make you feel more rested even on the same amount of sleep. In this …
How to slow or reverse graying of hair? | Masterjohn Q&A Files #321
Question: How to slow greying of hairs and potentially reverse it? Short Answer: What works for any given individual will likely be to find the weakest link and fix it, from among the following systems: the signaling of energy abundance (body fat, insulin sensitivity, thyroid hormone, adequate protein, individualized meeting of carbohydrate needs, good management of psychosocial …
Phosphatidylcholine and TMAO | Masterjohn Q&A Files #312
Question: If I’m at risk of heart disease and phosphatidylcholine increases my TMAO, should I stop the supplement? Short Answer: On a scale of one to ten, my concern about TMAO and cardiovascular disease is a three. There are thousands of things that should be given equal weight as potential contributors to heart disease, but TMAO gets …
Why would someone not tolerate methyl donors even if they need them? | Masterjohn Q&A Files #306
Short Answer: I believe most methyl donor intolerances are a result of deficiencies in the glycine buffer system, which requires glycine, vitamin A, fasting (glucagon), androgens, riboflavin, unmethylated folate (THF), and iron. No one should expect to tolerate 30 milligrams of folate, however, and there is almost never a reason to use doses that high.
Balancing Vitamin C and Glutathione: Final Report
Maintaining good GSH status is always important to protect high-dose C from generating oxalate and may often be important for preventing it from acting as a pro-oxidant. Cancer is an exception. In my preliminary report, I voiced the concern that high-dose vitamin C could deplete glutathione and worsen nitric oxide toxicity when not properly balanced with …
Recording and Transcript of the July 13, 2022 AMA
Glycine problems, deficiency signs when lab tests are normal, the 3 phases of fasting & what kicks you out, lipoic acid & methylation, sulfur SIBO that always comes back, heat intolerance, and more. Time Stamps 00:01:57 Does folate have any function in the fed state? 00:03:30 How do I know if my digestive enzymes are helping or …