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Do Ketogenic Diets Lower Glutathione? | Masterjohn Q&A Files #169

Question: Do Ketogenic Diets Lower Glutathione? And so what a ketogenic diet does is put you in a low insulin to glucagon ratio longterm and the insulin to glucagon ratio is what is used for the body to perceive whether it has enough energy to invest in making glutathione. And so the reason the liver’s …

Why do I have a high LDL-C when my diet is on point? | Masterjohn Q&A Files #168

Question: Why do I have a high LDL-C when my diet is on point? Generally in the presence of insulin sensitivity, more carbohydrates, less fat will lower LDL, but in the presence of insulin resistance, more carbohydrate will sometimes raise LDL. And if the LDL is only a little bit out of range and the …

Can protein replete glycogen on a low-carb diet? | Masterjohn Q&A Files #167

Question: Can protein replete glycogen on a low-carb diet? Yes, it’s possible. And I don’t know exactly what the dosing is, but I think it’s totally possible. It comes at the risk, I don’t want to say risk, but at the downside of creating a lot more ammonia. But I think it’s quite possible. I …

Creatine: do the benefits outweigh the risks for a mid-30s male? | Masterjohn Q&A Files #166

Question: Creatine: do the benefits outweigh the risks for a mid-30s male? I think that there are borderline no risks to creatine supplementation. I know some people get bloated from it that usually passes. Anecdotally, some people get insomnia. I think if nutrients are balanced and you just stick with it, that’ll go away. There’s …

How important are MAT1A SNPs to methylation? | Masterjohn Q&A Files #165

Question: How important are MAT1A SNPs to methylation? These in principle, could reduce the activation of methionine, but I don’t know that there are any studies that have looked at whether that’s the case. And so, just because a SNP isn’t a gene doesn’t mean that it reduces the activity of that gene. In fact, …

How to increase red blood cell magnesium content? | Masterjohn Q&A Files #164

Question: How to increase red blood cell magnesium content? Well, the first thing you want to do is look at your serum levels. And if your serum levels are low, you want to look at your urinary levels. And if your serum levels are not low or especially, if your serum are high, then you …

Why would ferritin rise on a low-carb diet when iron status is stable? | Masterjohn Q&A Files #163

Question: Why would ferritin rise on a low-carb diet when iron status is stable? Well, they sound copper deficient because copper is needed to mobilize iron out of ferritin. Copper is most abundant in plant foods, except that it’s also very rich in liver. And it’s pretty decent in a number of shellfish, but on …

What are the best practices for nutrient absorption? | Masterjohn Q&A Files #162

Question: What are the best practices for nutrient absorption? Large meals and fat soluble vitamins. Large meals are the ally of fat soluble vitamin absorption. Fat absorption from poor fat digestion, is the enemy of not only the absorption of fat soluble nutrients, but also the absorption positively charged minerals. There might a few of …

What’s the best prenatal nutrition? | Masterjohn Q&A Files #161

Question: What’s the best prenatal nutrition? The things that sort of stick out to me are, you don’t want to be Vitamin A deficient or Vitamin A toxic, so you’re right in the middle of the range. You really don’t want to be deficient in anything. Everyone knows about folic iron which is really important, …

Supplement Timing and Food Combining for Zinc? | Masterjohn Q&A Files #160

Question: Supplement Timing and Food Combining for Zinc? So for zinc and food, the main issue is that, my guess is that a carnivore meat based meal would probably enhance zinc absorption, but that’s never really been tested. There’s some controversy in the field over whether you should take zinc on an empty stomach or …