Question: Are there safety concerns in supplementing cyanocobalamin rather methylcobalamin in those with MTHFR polymorphisms? If you’re concerned about methylation-related issues, you would want to be careful with methylcobalamin supplementation in a way that you would not need to be careful about hydroxocobalamin supplementation. If you don’t have a specific methylation-related goal, then I think …
If you feel sick, what are the chances it’s the coronavirus? Researchers from the Los Angeles Departments of Public Health and Health Services and the Los Angeles County and University of Southern California Medical Center tested everyone who presented with mild flu-like illness to the emergency room or urgent care on March 12, 13, 15, …
A new study (as with virtually all circulating information on COVID-19, not yet peer-reviewed), shows that ACE2 can easily explain why smoking is correlated with worse outcomes in COVID-19. Background ACE2 is an enzyme whose normal role in our physiology is to lower our blood pressure, and to prevent damage to tissues from fibrosis (laying …
Question: What about pyroluria and measuring kryptopyrroles? I think it’s fairly harmless to increase zinc and B6 as a test of whether that’s true and see if you get results from it. But I wouldn’t treat it like a diagnostic value because no one has followed up any science on that disorder in the decades …
Question: How to manage blood levels of omega-3 and omega-6 fatty acids. I don’t specifically want to look at the omega-3-to-omega-6 ratio. The AA/EPA ratio, I do not believe in wanting to get it low enough to prevent inflammation. I don’t believe in using it that way. But I do believe that if it were …
New research suggests SARS-CoV-2 infects the throat, which makes important differences in how I will approach prevention. Why This Matters When I first wrote The Food and Supplement Guide for the Coronavirus, I took the position that SARS-CoV-2, the coronavirus that causes COVID-19, was most likely mainly infecting the lung without infecting parts of the upper …
Question: Can PEMT genetics cause fat malabsorption, mineral deficiencies, and oxalate problems? First of all, saponification of minerals, the point here is that if you have malabsorption of fat, the fatty acids are going to bind to any positively charged minerals in your diet. This has been particularly well studied in preterm infants where the …
As I explained in the last two updates (here and here) I’ve been studying hydroxychloroquine and chloroquine largely because I’m investigating whether their mechanisms shed any light on whether quercetin (rich in onions, nuts, and a variety of vegetables) and EGCG (abundant in green tea), are antiviral toward SARS-CoV-2 (the coronavirus that causes COVID-19) by acting …
As I explained yesterday, the reason I’m interested in hydroxychloroquine and chloroquine is because I’m investigating whether these, like quercetin and EGCG, are antiviral by acting as zinc ionophores, in which case I might add quercetin and EGCG to the protocol in The Food and Supplement Guide for the Coronavirus. A zinc ionophore is a …
The reason I’m interested in hydroxychloroquine and chloroquine is many people are claiming that these are effective against the coronavirus because they help bring zinc into cells, and the zinc kills the virus, and others have argued that since quercetin and EGCG do the same thing, these also would be effective for prevention or treatment …