Question: Can you give any suggestions for increasing delta-6 desaturase activity? There’s a bunch of nutrients involved in that, so many that you basically just need to do a comprehensive nutritional screening for whether something is missing there. You might just have low activity by genetics. It’s probably not worth solving that problem. The big …
Question: What are the pros and cons of boosting sulforaphane? Sulforaphane, the nice thing is it promotes detoxification. The bad thing is it raises the need for iodine. I don’t know what ratio to take, but you definitely want to make sure that you’re getting some kind of iodine into your diet, whether it’s through …
Question: Is it true that we can’t absorb more than 1.5 grams of creatine at one time? I don’t think that’s true. From what I looked at, it looked like the absorption of creatine was really, really good. I don’t know if someone was arguing maybe that we don’t retain more than that. But I …
Question: NMN vs. NR: What’s better? And is TMG necessary? Yeah. There are no human studies looking at NMN and how it’s metabolized. There are studies of NR. No one has showed any positive benefits of supplementing NR in humans yet, but they haven’t really done any long-term studies or looked at many things, and …
Question: What to do about cataracts. I believe that cataracts in the eye are largely driven by the glycation of lens proteins. The glycation of lens proteins is largely driven by methylglyoxal, which I did my doctoral dissertation on. In direct contradiction to much of the low-carbohydrate literature, glycation is not all driven by carbs. …
Question: If free T3 looks good, why is TSH still a little high? Why hasn’t the T3 brought it down enough? Your thyroid gland makes thyroid hormone. Thyroid hormone increases your metabolic rate and does a lot of related things. Your hypothalamus is governing that by controlling your pituitary, the master endocrine gland, and its …
Question: What food supplements and training programs are good for developing muscle mass? Overwhelmingly, what matters for muscle mass is working out, eating enough protein, and eating enough calories. You want to try and hit 10-20 sets per muscle group per week with eat set hitting within 80% of failure. So, if your doing a …
Question: Should I manage my total cholesterol of 305 just for my doctor or should I be doing it for my own sake? If so, how should I do it? You should want to improve your lipid profile for a lot more than to please your doctor. Let’s revisit this from a cholesterol skeptic point …