Question: neither my mother nor myself respond to T3 supplementation (cytomel; up to 140 mcg/d). Body temp remains low and reverse T3 stays normal. Could you discuss the factors that might interfere with thermogenesis in response to T3, and offer considerations how to improve this? Having normal levels of reverse T3 tells you that the …
Question: “What are your top three non-nutrient factors that prevent someone from entering beta-oxidation or ketogenesis? I mean like sleep disruption.” Top three non-nutrient factors? Unless you are taking a drug that prevents lipolysis, then they aren’t non-nutrient. The overwhelming things that govern those are carbohydrate and fat intake. You eat more fat, you have …
Question: “Any recommendations for peripheral neuropathy? Testing vitamin B, lion’s mane?” First of all, there is no such thing as vitamin B. I’m not trying to be a nitpick, but there’s literally almost a dozen B vitamins, with different tests, that do different things. So, I think it’s important to establish a habit of never …
Question: “If cholesterol, LDL-P, and oxidized LDL are high, the sterol panel is normal, and TGs are great, would you suspect clearance of the particles driven by LDL receptor in the liver is the issue, and what would you recommend to boost LDL-R?” Yes, it sounds like you should target LDL-R. The big regulators of …
Question: “What are your recommendations on magnesium supplements and dosage?” My opinion is that most people shouldn’t be supplementing with high doses of magnesium. I think if you’re going to supplement with more than 400 milligrams a day, you should be testing your magnesium status, and you should be making decisions on that. I think …
Question: “Calcium score, is there a way to treat one’s calcium score and get it to zero?” ⇒ No, you don’t treat the calcium score. You take the calcium score as indicative of what’s going on in atherosclerosis, and you treat that. The goal, I think, is calcium score equals zero. No, that’s a bad …
Doctor Garrett Smith, ND, a naturopath, recently purported to analyze my health, making inferences from blog posts, pictures, and comments I’ve made on the internet, concluding that I am suffering from vitamin A toxicity. Smith runs a “comprehensive Poison/’Vitamin A’ Detox program” and lists an invitation to contact his office to work with him as …
Question: “What do you think of alternative testing like hair mineral analysis or SpectraCell?” I’m against SpectraCell on the basis of, it’s not validated. I gave more details in a podcast episode “What Makes a Good Marker of Nutritional Status?” and you can find that at chrismasterjohnphd.com/marker. Hair mineral analysis; I like hair mineral analysis …
Question: How do I address edema? Edema is basically going to be caused by excess salt retention in the body. The reason is that with the exception of very extreme scenarios, your body is going to tightly regulate the sodium concentration of the water in your body, and sodium draws water. Now, that’s not to …
Question: “How do you determine if you’re getting enough protein? I heard Dr. Stephen Phinney say, for those on a keto diet, if ketones are greater than 3 on a regular basis, then it’s a sign you’re not getting enough protein.” First of all, why are you on a ketogenic diet? If your purpose is …