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The full episode is only available to paid subscribers of Harnessing the Power of Nutrients

2. Activation Energy and Enzymes

Lesson 2 of Masterclass With Masterjohn: Energy Metabolism.
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The second MWM energy metabolism looks at how we use enzymes to exert exquisite control over what happens inside our bodies.

If the second law of thermodynamics holds that entropy is always increasing, why don't we reach maximum entropy right away? Why do we observe any order at all?  The activation energy represents the resistance to change that can be found in any substance. We exploit the concept biologically by maintaining a body temperature that provides insufficient energy for most relevant reactions to go forward without catalysis, and imposing upon this backdrop an expansive repertoire of enzymes that can, in a regulated fashion, lower the energy barriers sufficiently for reactions to go forward.

This lesson looks at how they do that, and how we regulate their activity.

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Transcript, Slides, References, Further Reading

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The full video is for paid subscribers

Harnessing the Power of Nutrients
Masterclass With Masterjohn: Energy Metabolism
This is a course with 39 lessons on the biochemistry of how we burn carbohydrate and fat for fuel.
Authors
Chris Masterjohn, PhD