Two new preprints* on vitamin D were released on May 5, and I analyze them in this update. Background So far I have covered vitamin D in three issues of this newsletter: My Response to Rhonda Patrick on Vitamin D and COVID-19 Update on Vitamin D and COVID-19 Using the First Observational Study Released The …
Remdesivir Is Probably a Reproductive Toxin, and Its Benefit Is Unclear
On April 29, the NIH’s National Institute of Allergy and Infectious Disease (NIAID), headed by Dr. Anthony Fauci, announced promising preliminary results of its clinical trial testing the effect of remdesivir in COVID-19 patients. The study has not been released even as a preprint.* Fauci told the press that he chose to speak about the …
Naproxen (Aleve), Clotting, Viral Growth, and COVID-19: Preliminary Evidence
On April 22, I reported on the first large series of post-mortem analyses that suggested blood clots within the small arteries of the lungs may be at the root of the COVID-19 hypoxemia (low blood oxygen). Since then, New York City doctors have reported strokes occurring in COVID-19 patients under the age of 50, including …
New Evidence That Interferon Can Be Harmful in COVID-19
In The Food and Supplement Guide for the Coronavirus, I predicted that interferon contributes to the lung pathology of COVID-19 and could worsen the risk of severe disease and death. As a result, I screened all of the antiviral and immune support supplements I was considering for inclusion and recommended against anything that appeared to …
Update on Vitamin D and COVID-19 Using the First Observational Study Released
Today I was made aware of a preprint* that was most recently revised yesterday with specific data on vitamin D status. This is the first observational study that has, to my knowledge, addressed how vitamin D levels correlate with COVID-19 severity. A researcher from the Philippines used the data from three South Asian hospitals to …
Machine Learning From 8.2 Million Mayo Clinic COVID-19 Clinical Notes Identifies Early Symptoms
On April 7, I reported the results of a study using a mobile app to identify which self-reported symptoms best predict a confirmable case of COVID-19, giving central importance to the loss of smell (anosmia) or the loss of taste (ageusia), with lesser importance to fever, loss of appetite, cough, diarrhea, and fatigue. The study …
Small Blood Clots May Be at The Root of the COVID-19 Hypoxemia
At the end of March, a New York City doctor drew massive attention with his claim, published in a YouTube video, that COVID-19 was more similar to altitude sickness than to acute respiratory distress syndrome (ARDS), and that it was being treated the wrong way. At the root of his claim was that ARDS patients …

What are causes for night sweats in men?| Masterjohn Q&A Files #111
Question: What are causes for night sweats in men? Carrie: Oh. Well, it can be hormonal just like it can be for women. I test all the same hormones in men. I check their thyroid with night sweats. I definitely even check the same thing. I check cortisol and I do norepinephrine markers with night …

Why do I wake up early every morning when I’m depressed? | Masterjohn Q&A Files #109
Question: Why do I wake up early every morning when I’m depressed? Carrie: Now, with depression, it’s heavily studied if you have an elevated or excessive cortisol awakening response, meaning you go higher, your spike is higher and more dramatic than the average bear, then your risk for morning depression is much higher. The reason …
My Response to Rhonda Patrick on Vitamin D and COVID-19
On September 13, 2020, I made an important update to my position, which is included at the end of the article. You can click through to it directly using this link. Yesterday, Dr. Rhonda Patrick, PhD, of Found My Fitness released an email to her list with the subject “Vitamin D may reduce susceptibility to …