In my opinion, it's best to just avoid whatever could possibly be a health risk. Your safety is never to be taken for granted, no matter the circumstances.
This is a very interesting discussion, and something that has always been up for debate. Heart problems have various root causes, and it's hard to single out dietary choline for that.
So if you don't happen to have enough carnitine to burn the lipids, that would likely cause a higher blood level of Choline, wouldn't it? So this study possibly could be detecting carnitine deficiency and not choline over-abundance…
I like the Phosphatidylcholine supplements which contain a range of different phospholipids. I agree with Chris, the closet we can get to food the better.
Personally, while I'm less than entirely convinced of this mechanistic link to heart disease, I would avoid any choline supplements that do not use phosphatidylcholine, since this is by far what is overwhelmingly found in food.
My multivitamin has choline bitartate in it (a large portion). Should I be worried based on the Ziesel et al (1983) findings about choline chloride and choline stearate.
Gut flora metabolism of phosphatidylcholine
promotes cardiovascular disease full text PDF
There is a link between Inflammatory bowel disease and coronary artery disease and so this paper discussing the role of different Role Of Gut Flora In Inflammatory Bowel Disease- A State Of Art may set some minds at rest.
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In my opinion, it's best to just avoid whatever could possibly be a health risk. Your safety is never to be taken for granted, no matter the circumstances.
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This is a very interesting discussion, and something that has always been up for debate. Heart problems have various root causes, and it's hard to single out dietary choline for that.
So if you don't happen to have enough carnitine to burn the lipids, that would likely cause a higher blood level of Choline, wouldn't it? So this study possibly could be detecting carnitine deficiency and not choline over-abundance…
I like the Phosphatidylcholine supplements which contain a range of different phospholipids. I agree with Chris, the closet we can get to food the better.
Jeremy,
Personally, while I'm less than entirely convinced of this mechanistic link to heart disease, I would avoid any choline supplements that do not use phosphatidylcholine, since this is by far what is overwhelmingly found in food.
Chris
My multivitamin has choline bitartate in it (a large portion). Should I be worried based on the Ziesel et al (1983) findings about choline chloride and choline stearate.