How to use carbs and glycine for sleep. | Masterjohn Q&A Files #287

Short Answer: To get adequate raw material for melatonin synthesis in the brain, carbs can come any time of day and are best if high-glycemic. To suppress brain histamine levels, carbs in the evening, with low protein and relatively low fat, is best. From among protein, collagen is best at night for the glycine. Watch …

Why does methylfolate act as the off-switch for the glycine buffer system? | Masterjohn Q&A Files #272

Short Answer: When we have too many methyl groups, MTHFR is shut off and methylfolate is not produced. Therefore, methylfolate acts as a signal that we do not have enough methyl groups, and shuts off the glycine buffer system, which is only active when we have too many methyl groups.  Watch the video or listen …

Why do glycine and salt help with sleep? | Masterjohn Q&A Files #245

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt  Plenty more at https://chrismasterjohnphd.com/support! Question: Why do glycine and salt help with sleep? The glycine is probably working primarily by acting as an inhibitory neurotransmitter and lowering core body temperature to promote …

Why is methylfolate the off-switch for the glycine buffer system? | Masterjohn Q&A Files #239

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt  Plenty more at https://chrismasterjohnphd.com/support! Question: Why is methylfolate the off-switch for the glycine buffer system? The reason is that generally in the fed state, you have lots of incoming methionine. And so …

Is TMG a good source of glycine? | Masterjohn Q&A Files #225

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt  Plenty more at https://chrismasterjohnphd.com/support! Question: Is TMG a good source of glycine? And so glycine is a methyl buffer. So it’s not the default that one extra methyl group from TMG is …