Question: How much iron can we absorb at once? Short Answer: High-dose iron will produce more total absorbed iron, but will also leave more in the gut, which could cause constipation or disturb the gut microbiome. If desperate for quick relief, 200 milligrams per day of iron taken in the morning will work faster than lower doses …
Question: What cofactors are needed to synthesize and recycle BH4? Short Answer: Zinc, magnesium, potassium, and niacin are the cofactors needed for the synthesis and recycling of BH4. Folate and methylation are not involved, though high-dose folate or folic acid could hypothetically hurt BH4 recycling since both are recycled by dihydrofolate reductase (DHFR).
Question: Is it important to get vitamin D sulfate specifically from the sun? Short Answer: It is important to get morning outdoor sunlight as close to every day as possible for your circadian rhythm, and to get some exposure to unprotected sunlight during the day when UV is available, but at doses less than needed to cause …
Question: If I don’t want to hurt my omega 6 status through my omega 3 intake, how do I do that? Is it simply a question of taking them at separate times? Or is it a question of dose? And if it is a question of dose, how do I know when to start eating fish …
Question: If I don’t want to hurt my omega 6 status through my omega 3 intake, how do I do that? Is it simply a question of taking them at separate times? Or is it a question of dose? And if it is a question of dose, how do I know when to start eating fish …
Question: Can plant foods and their phytochemicals be used to reduce arterial plaque? Short Answer: Yes, but if you don’t have specific intolerances to plant compounds the best thing to do is simply aim to meet your vitamin and mineral targets from a diet rich in fruits, vegetables, herbs, and spices, rather than trying to use specific …
Question: What can be done about twitching? Short Answer: Most twitching will be driven by glutamate/GABA balance or acetylcholine regulation, and the most likely nutritional issues are any of the electrolytes or any factor that influences energy metabolism. The best way to address it is to consider the conditions that influence it and then trial and error …
Question: If undercarboxylated osteocalcin has health benefits, and vitamin K2 decreases it, what does that mean for K2 supplementation? Short Answer: Vitamin K2 helps secure osteocalcin in bone matrix, where it is decarboxylated and released as an endocrine hormone in response to certain stimuli. When released, it acts to optimize insulin secretion, insulin sensitivity, fuel use during …
Question: If I’m at risk of heart disease and phosphatidylcholine increases my TMAO, should I stop the supplement? Short Answer: On a scale of one to ten, my concern about TMAO and cardiovascular disease is a three. There are thousands of things that should be given equal weight as potential contributors to heart disease, but TMAO gets …
Question: How do I fix low blood sugar on vegan keto? Short Answer: Consider how important it is for your ketones to be elevated. Most likely you need to eat more protein, which will lower your ketones. I would aim for a minimum of 0.8 grams per kilogram of ideal bodyweight and consider using 1.2 grams per …