A French hospital published results a few days ago of a non-randomized controlled trial testing hydroxychloroquine as a treatment for COVID-19. This looks like both good and bad news. The upside: 200 mg hydroychloroquine sulfate three times a day for ten days reduced the presence of the virus in nose and throat swabs to zero …
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Could an elevated BUN indicate protein malabsorption and low stomach acid? | Masterjohn Q&A Files #93
Question: Could an elevated BUN indicate protein malabsorption and low stomach acid? I get the Heidelberg test. That’s the only accurate way to assess stomach acid. If you want to do something else, it would be better to use the kitchen techniques, like take half a teaspoon of baking soda and see how long you …

Are bilirubin and uric acid useful markers of antioxidant defense and oxidative stress? What are better markers? | Masterjohn Q&A Files #92
Question: Are bilirubin and uric acid useful markers of antioxidant defense and oxidative stress? What are better markers? I think intracellularly where most of antioxidant support is highly relevant, then they’re not that big a deal. In the plasma, they can be a big deal. It’s quite possible that uric acid is one of the …

Does it matter what form of B12 you take? | Masterjohn Q&A Files #91
Question: Does it matter what form of B12 you take? Cyanocobalamin is cheap and there’s not really any clear evidence that it’s harmful, but I just don’t like the idea that it is cobalamin bound to cyanide. It’s not found in the food supply. Forming cyanocobalamin and peeing it out is actually one of the …

Is it useful to measure urine pH? | Masterjohn Q&A Files #90
Question: Is it useful to measure urine pH? The urine pH is telling you the acid burden that your body has been subjected to. It’s telling you, you can make an inference about the compensations that your body has had to engage in. You can also make an inference about the limitations of your body …

Why AGEs and deficient insulin signaling are the main problem in diabetes. | Masterjohn Q&A Files #89
Question: Why AGEs and deficient insulin signaling are the main problem in diabetes. The reason that methylglyoxal, which I did my doctoral dissertation on, the reason that methylglyoxal, which is quantitatively the most important form of advanced glycation end products in diabetics, the reason that it is elevated is not because of hyperglycemia. It’s because …

Nutritional recommendations for MTR and MTRR polymorphisms. | Masterjohn Q&A Files #88
Question: Nutritional recommendations for MTR and MTRR polymorphisms In the methylation cycle, I’ve talked a lot about MTHFR, which helps finalize the methyl group of methyfolate. But then folate has to donate that methyl group to vitamin B12 in order for vitamin B12 to donate it to homocysteine. In that process, that’s how you …

Nutrition for children with ADHD. | Masterjohn Q&A Files #87
Question: Nutrition for children with ADHD. In adults 100 to 800 milligrams per day has been used in a couple studies showing effects in the brain. One of the things that’s going wrong in ADHD is that the brain is not getting dopamine’s signal that something is valuable enough to keep paying attention to it. …

Nutrients important for neuroregeneration. | Masterjohn Q&A Files #86
Question: Nutrients important for neuroregeneration. Iron, phosphorus, and sulfate are very important for regenerating nerves. Magnesium. Acetylcholine is a major factor in regeneration of nerves, and so choline is important. If you were to use a supplement, alpha-GPC would be the ideal choline supplement to use because it’s superior at generating acetylcholine. Vitamin A and …

Advice for what to do after suffering a transient ischemic attack | Masterjohn Q&A Files #85
Question: Advice for what to do after suffering a transient ischemic attack A TIA, a transient ischemic attack, is like a mini stroke, but they all kind of fall into the same category where the development of plaque is a very significant part, is the major thing disposing you to having an event like that. …