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67 Comments on When Fat Burns In the Flame of Lean Muscle Mass — Better Put That Butter Either on Steak or Potatoes

When Fat Burns In the Flame of Lean Muscle Mass — Better Put That Butter Either on Steak or Potatoes

My last post was political and got 17 comments just in the first six hours.  I suppose that means I’m due for another post about religion, or one about sex.  Given Stephan Guyenet’s recent post about the dangers of hyperpalatability, though, I’m inclined to obey the proverb “don’t take too much honey” and delicately sprinkle …

33 Comments on Fructose, Public Policy, and The Low-Fat Re-Education Camp (Short Post)

Fructose, Public Policy, and The Low-Fat Re-Education Camp (Short Post)

Here’s another short post in honor of my readers with ADHD. One subject that came up in Dr. Lustig’s recent interview on “Sugar and Health” is the need to formulate public policy in order to reduce fructose consumption. I think, as advocates of real traditional foods that will invariably have differing political dispositions, we need to …

27 Comments on Let Us Honor Ancel Keys, Our Patron, As We Cherry Pick Studies to Bash Fructose (Revised and Extended)

Let Us Honor Ancel Keys, Our Patron, As We Cherry Pick Studies to Bash Fructose (Revised and Extended)

My apologies to anyone who received this in their RSS feed on Thursday as a teaser.  I have now revised and extended it to include several studies showing that diet-induced obesity can be achieved in rats and mice without using any sugar at all, and have included a clearer conclusion. Ancel Keys is best known …

66 Comments on What No One Is Saying About Zonulin — Is Celiac About More Than Genes and Gluten?

What No One Is Saying About Zonulin — Is Celiac About More Than Genes and Gluten?

In my last gluten post, I discussed why the ex vivo results of Dr. Fasano’s 2006 study cannot logically be construed to show that gluten causes leaky gut in people without celiac disease, and why the available evidence suggests that people considered to have non-celiac gluten sensitivity do not have leaky gut. Nevertheless, this study …

21 Comments on How to Properly Interpret Ex Vivo Studies — Gluten and Leaky Gut As an Example

How to Properly Interpret Ex Vivo Studies — Gluten and Leaky Gut As an Example

There seems to be some confusion about how to appropriately interpret ex vivo studies, which are studies that are not conducted in a living organism. Worse than that, there appears to be a common and rather dramatically misleading presentation of the data in Dr. Allesio Fasano’s excellent study linking gluten to zonulin production.  But I’ll …

8 Comments on How a Study Can Show Something to Be True When It’s Completely False — Regression to the Mean

How a Study Can Show Something to Be True When It’s Completely False — Regression to the Mean

In a previous post, “The Great Unknown: Using the Statistics to Explore the Secret Depths of Unpublished Research,” I discussed one way a study can show something to be true when it’s false, or vice versa. If some nutrient or drug has a “true” biological effect, and we repeat many studies of the phenomenon, we …

67 Comments on Getting Better Sleep — Cool, Dark, And Lots of B6, Carbs, Calories, and Fat

Getting Better Sleep — Cool, Dark, And Lots of B6, Carbs, Calories, and Fat

Chris Kresser and Paul Jaminet recently posted some sleeping tips.  A lot of other great bloggers write about sleep too, like Mark Sisson, Robb Wolf, and Stephan Guyenet.  I think sleep is really important, and I’ve had a lot of sleeping problems in the past, some of which I still occasionally struggle with, so I’m going to …