Question: How to slow greying of hairs and potentially reverse it? Short Answer: What works for any given individual will likely be to find the weakest link and fix it, from among the following systems: the signaling of energy abundance (body fat, insulin sensitivity, thyroid hormone, adequate protein, individualized meeting of carbohydrate needs, good management of psychosocial …
What cofactors are needed to synthesize and recycle BH4? | Masterjohn Q&A Files #319
Question: What cofactors are needed to synthesize and recycle BH4? Short Answer: Zinc, magnesium, potassium, and niacin are the cofactors needed for the synthesis and recycling of BH4. Folate and methylation are not involved, though high-dose folate or folic acid could hypothetically hurt BH4 recycling since both are recycled by dihydrofolate reductase (DHFR).
Balancing Vitamin C and Glutathione: Final Report
Maintaining good GSH status is always important to protect high-dose C from generating oxalate and may often be important for preventing it from acting as a pro-oxidant. Cancer is an exception. In my preliminary report, I voiced the concern that high-dose vitamin C could deplete glutathione and worsen nitric oxide toxicity when not properly balanced with …
Lipoic Acid Saps Methyl Groups
At what dose should we be concerned, and what can we do about it? Yesterday, I held a live Q&A with Masterpass members, and one of the questions that came up was whether we should be concerned about alpha-lipoic acid supplements hurting methylation as described in this rat study from 2010. After searching among the papers citing this study, the Examine.Com …
Recording and Transcript of the June 16, 2022 AMA
SIBO; CGM/HbA1c conflicts; vitamin C, copper, and histamine; reishi, curcumin, and testosterone; magnesium problems; vitamin toxicity; fat malabsorption; tinnitus; baking glycine; much more. Time Stamps 03:41 What to Do About Persistent SIBO? 20:03 If your CGM conflicts with your HbA1c 27:30 Are there toxicity concerns for vitamin C and copper used for histamine? 33:55 Are there toxicity concerns for …
The Spike Protein As a Pore-Forming Toxin
The spike protein pokes holes in cell membranes at concentrations much lower than those achieved with vaccination, contributing to COVID-like illness and mitochondrial damage. But is the J&J immune? This is not medical advice. Please see the full disclaimer at the bottom. The spike protein from the COVID vaccines is found in humans for at least …
The Best of 2021
As we look forward with hope and determination toward a wonderful 2022, let us first briefly look back on the best of 2021. Here I’m posting the ten most popular posts on my web site from the last year. Perhaps it’s worth revisiting one of these if you’ve forgotten them, or maybe this will draw …
How to Fix a Sore Throat
Something is going around — perhaps in many cases a mild case of omicron — that is leaving people with isolated sore throats, and sore throat seems to be sticking out as a COVID symptom this time around as well. I had a version of this, and many around me have as well. So, here’s …
Across what timeframe should we diversify foods? | Masterjohn Q&A Files #270
Short answer: for most nutrients, hitting within 75% of your target on a daily basis and hitting your target on a weekly average basis is sufficient. Fat-soluble vitamins may be less important to hit 75% every day, and some nutrients like zinc and B12 have special considerations for timing. Watch the video or listen to …
Vitamin D and COVID-19: The Current State of the Evidence
Note: You can watch my presentation based on this research from the 2021 Ancestral Health Symposium here, watch a much longer video that covers missing slides and answers questions about the talk here, download a PDF of my slides here, and see a short list of minor corrections to the presentation in note 1. In a …