Analia Camarasa asked this question on Facebook: Ever since you’ve mentioned PTH on your podcast we’ve been measuring it in the office. It’s nice to see that when patients come in on high doses of D supplementation their PTH is maximally suppressed, as it should be. I wish you could talk about the outliers briefly, …
This lesson looks at the fundamental principle that atomic oxygen is the limiting factor for the release of carbon dioxide in metabolism, and when we don’t have enough we take it from water. This will become very relevant when we cover fats versus carbohydrates, because they consume different amounts of water and release different amounts …
Vitamin D deficiency and calcium deficiency look very similar, and poorly interpreted blood tests can easily mislead us into taking the wrong supplements. Here’s how to tell them apart. How to watch it: Watch it on Facebook. Watch it on YouTube. How to share it and show it love: Share it on Facebook. Give it …
This lesson addresses the curious case of why CoA makes a brief cameo in the citric acid cycle during the formation of succinyl CoA only to leave again in the next step. We dig into the chemistry underlying the high-energy thioester bond that CoA forms with acyl groups, which explains more broadly one of the …
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Glutamate is the most abundant amino acid in the diet, but is usually bound up in proteins. In its free form, it contributes to the umami taste, which is the savory flavor associated with meat and mushrooms. Long, slow cooking and fermenting can both bring out this flavor.⠀ Unfortunately, some people don’t tolerate glutamate well. …
This complex is so rich in biochemical concepts and relevance to health and disease. Having done the dirty work of looking at its organic chemistry mechanisms in the last lesson, here we explore broadly applicable biochemistry principles like energetic coupling and substrate channeling. We look at how thiamin deficiency, oxidative stress, arsenic, and heavy metal poisoning …
Here are the 5 best ways to lower cholesterol naturally. How to watch it: Watch it on Facebook. Watch it on YouTube. How to share it and show it love: Share it on Facebook. Give it a thumbs up on YouTube. Like it on Instagram. Retweet it on Twitter. Want a Transcript? CMJ Masterpass holders can …
The alpha-ketoglutarate dehydrogenase complex is marvelously complex and incredibly rich in details that are relevant to the big picture of metabolism and to many issues of health and disease. Today, we break down what actually happens so that we can spend all of Wednesday’s lesson discussing the rich array of relevant principles it brings to …