Showing: 1 - 6 of 12 Articles
Chris Masterjohn answered questions about saturated fat, obesity, inflammation, Ray Peat, Andrew Kim, sugar, antioxidants, Brian Peskin, tests for folate status, accidental gluten exposure, fecal IgA testing, protein, muscle mass, longevity, ketosis, carbs, the total-to-HDL-cholesterol ratio and the triglyceride-to-HDL-C ratio.

Mastering Nutrition Episode 14: I Came LIVE On Facebook So YOU Could Ask Me Anything, and THIS Is What Happened!

This past Saturday I went on Facebook Live for the first time ever so you could ask me anything about health, fitness, and nutrition. It was incredible! Thank you to everyone who came and asked questions! Below you can watch the video or listen to the audio recording as a podcast. Listen on ITunes or …

Methylglyoxal regulates glycolysis in a way that prevents dangerous accumulation of glyceraldehyde, and that conserves glucose during carbohydrate restriction. Its rise on a low-carb Atkins diet makes physiological sense because it conserves glucose and even allows gluconeogenesis from fatty acids. Nevertheless, high methylglyoxal levels causally contribute to diabetes, and this seems to be a stress response that should not be chronically elevated.

Mastering Nutrition Episode 13: Wait a Second, Is Glycation Actually GOOD For You?

  In this episode, I wrap up glycation week by discussing why glycation may play essential physiological roles in the body. In the early days of methylglyoxal research, Albert Szent-Gyorgyi, who won the 1937 Nobel prize in Physiology or Medicine for his discovery of vitamin C and critical steps in energy metabolism, saw the molecule …

Hba1c is confounded not only by red blood cell turnover, but also by the activity of fructosamine 3-kinase (FN3K). Surprisingly, lower Hba1c due to higher FN3K activity could actually mean MORE glycation if your downstream metabolism of 3-deoxyglucosone is not in order.

Mastering Nutrition Episode 012: What Is Measuring Our Hba1c REALLY Telling Us About Our Blood Glucose and Diabetes Risk?

In response to popular demand, this week is glycation week. In this episode, I discuss the strengths and limitations of using Hba1c to measure our cumulative recent exposure to blood glucose and diabetes risk. Many people will be familiar with the fact that variation in red blood cell turnover confounds this measurement. Less well known …

My Paleo f(x) presentation was on using fat-soluble vitamins to optimize sex hormones, but I also discussed the importance of body fat and carbohydrate intake for fertility and in this podcast I also discuss why using a low-carbohydrate diet to treat type 1 diabetes could negatively affect thyroid hormone and sex hormones.

Mastering Nutrition Episode 11: Paleo f(x) Grab Bag: Carbs, Sex Hormones, Type 1 Diabetes, and More

In this episode, I discuss some important insights from my Paleo f(x) talk and audience responses to it, including the potential dangers of treating type 1 diabetes with a low-carb diet, the importance of carbs and body fat for fertility and sex hormones, and why some people might have a great sex hormone profile on …

Dr. Chris Masterjohn talks about How to Know if Your Genetics Contribute to Your Sensitivity to Blue Light and Poor Sleep, and What to Do About it

Mastering Nutrition Episode 10: How to Know if Your Genetics Contribute to Your Sensitivity to Blue Light and Poor Sleep, and What to Do About it

In this episode, I show you how you can determine whether your genetics are contributing to your sensitivity to blue light, poor sleep, and poor daytime alertness, and what you can do about it. Specifically, I look at the research showing that variations in the gene for the vitamin A-dependent protein melanopsin underlie sensitivity to …

Dr. Chris Masterjohn talks about Balancing Calcium and Phosphorus in the Diet, and the Importance of Measuring Parathyroid Hormone (PTH)

Mastering Nutrition 9: Balancing Calcium and Phosphorus in the Diet, and the Importance of Measuring Parathyroid Hormone (PTH)

In this episode, I answer a listener’s question about whether I am worried about my phosphorus intake and whether a high phosphorus intake is ok as long as it is balanced by calcium. I describe the biochemistry and physiology of the system that regulates calcium and phosphorus, their distribution in foods, how to determine the …