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Is Whole Food Vitamin C Really Different? | Masterjohn Q&A Files #330
Question: Is whole food vitamin C superior to natural because it is part of a tyrosinase complex? Short Answer: Vitamin C is nearly ubiquitously distributed in…
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What's the Deal With Seed Oils? | Masterjohn Q&A Files #329
Question: What Is the Real Issue With Seed Oils? Short Answer: The main issue with seed oils is that they present an oxidative liability.…
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Is Hair Mineral Testing Useful? | Masterjohn Q&A Files #328
Question: How useful is hair trace mineral analysis (HTMA) for nutritional testing? Short Answer: Hair trace mineral analysis is included as an optional add-on in the…
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How to Find the Root Cause of Autoimmunity? | Masterjohn Q&A Files #327
Question: How do we find the root cause of an autoimmune condition? One example considered where the root cause is energy metabolism. Short Answer: Autoimmune conditions…
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Why Would Vitamin C cause muscle pain, joint pain, and brain fog? | Masterjohn Q&A Files #326
Question: Why Would Vitamin C cause muscle pain, joint pain, and brain fog? Short Answer: Acutely, vitamin C would likely cause these effects by…
Can NAC hurt your gut health? | Masterjohn Q&A Files #325
Question: Can NAC Hurt Gut Health When Used to Disrupt Biofilms? Short Answer: N-acetylcysteine or NAC can be used at a dose of 600 to 2,400…
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How can I protect against oxalates? | Masterjohn Q&A Files #324
Question: How can I protect against oxalates? Short Answer: Getting 300-400 mg calcium between food and supplements at each meal will minimize oxalate absorption. Maintaining postprandial…
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Why Should Postprandial Glucose Be Kept Under 140 mg/dL? | Masterjohn Q&A Files #323
Question: Why should postprandial blood glucose be kept under 140 milligrams per deciliter? Short Answer: When blood glucose rises above 140 mg/dL, this is the approximate…
What is the relationship between copper and estrogen? | Masterjohn Q&A Files #322
Question: What is the relationship between copper and estrogen? Short Answer: Estrogen moves copper from the mother’s bloodstream to the fetus during pregnancy. Its action at…
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How to slow or reverse graying of hair? | Masterjohn Q&A Files #321
Question: How to slow greying of hairs and potentially reverse it? Short Answer: What works for any given individual will likely be to find the weakest…
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How Much Iron Can We Absorb At Once? | Masterjohn Q&A Files #320
Question: How much iron can we absorb at once? Short Answer: High-dose iron will produce more total absorbed iron, but will also leave more in the…
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What cofactors are needed to synthesize and recycle BH4? | Masterjohn Q&A Files #319
Question: What cofactors are needed to synthesize and recycle BH4? Short Answer: Zinc, magnesium, potassium, and niacin are the cofactors needed for the synthesis and recycling…
Is It Important to Get Vitamin D Sulfate Specifically From the Sun? | Masterjohn Q&A Files #318
Question: Is it important to get vitamin D sulfate specifically from the sun? Short Answer: It is important to get morning outdoor sunlight as close to…
If I have a hereditary weakness in breaking down branched-chain amino acids, what cofactors do I need to consider, and do I need to restrict my protein when losing weight? | Masterjohn Q&A Files #317
Question: If I don’t want to hurt my omega 6 status through my omega 3 intake, how do I do that? Is it simply a…
How do I consume omega-3 without hurting my omega-6 status? | Masterjohn Q&A Files #316
Question: If I don’t want to hurt my omega 6 status through my omega 3 intake, how do I do that? Is it simply a…
Can plant foods and their phytochemicals be used to reduce arterial plaque? | Masterjohn Q&A Files #315
Question: Can plant foods and their phytochemicals be used to reduce arterial plaque? Short Answer: Yes, but if you don’t have specific intolerances to plant compounds…
What to Do About Twitching | Masterjohn Q&A Files #314
Question: What can be done about twitching? Short Answer: Most twitching will be driven by glutamate/GABA balance or acetylcholine regulation, and the most likely nutritional issues…
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Vitamin K2 and Undercarboxylated Osteocalcin | Masterjohn Q&A Files #313
Question: If undercarboxylated osteocalcin has health benefits, and vitamin K2 decreases it, what does that mean for K2 supplementation? Short Answer: Vitamin K2 helps secure osteocalcin…
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Phosphatidylcholine and TMAO | Masterjohn Q&A Files #312
Question: If I'm at risk of heart disease and phosphatidylcholine increases my TMAO, should I stop the supplement? Short Answer: On a scale of one to…
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Low Blood Sugar on Vegan Keto | Masterjohn Q&A Files #311
Question: How do I fix low blood sugar on vegan keto? Short Answer: Consider how important it is for your ketones to be elevated. Most likely…
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Brain Fog on Calcium, Vitamin D, or K2 | Masterjohn Q&A Files #310
Question: Why would vitamin D, vitamin K2, and calcium give me brain fog? Short Answer: Most likely by decreasing serum phosphorus. The solution is to balance…
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Why Plasma Zinc is the Best Marker of Zinc Status | Masterjohn Q&A Files #309
Short Answer: Plasma zinc is the single most important marker of zinc status. Urine zinc may decline faster in deficiency. Hair zinc increases with…
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Glutathione Intolerance: Getting to the Bottom of It | Masterjohn Q&A Files #308
Question: Why do many chronically ill people have an intolerance to glutathione, and what can be done at home to determine the cause? Short…
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Statins Vs. Sulfur for Heart Disease | Masterjohn Q&A Files #307
Short Answer: From the trials, statins seem to reduce heart disease risk and total mortality, but it is impossible to separate this from conflicts of…
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Why would someone not tolerate methyl donors even if they need them? | Masterjohn Q&A Files #306
Short Answer: I believe most methyl donor intolerances are a result of deficiencies in the glycine buffer system, which requires glycine, vitamin A, fasting (glucagon),…
Does whey protein hurt the kidneys or otherwise hurt our health? | Masterjohn Q&A Files #305
Question: Does whey protein hurt the kidneys or otherwise hurt our health? Short Answer: The main problem with too much protein, particularly animal protein, is that…
Does glucose handling in the brain decline with age? And if so, does this serve as a rationale to supplement with MCT oil to prevent cognitive decline? | Masterjohn Q&A Files #304
Does glucose handling in the brain decline with age? And if so, does this serve as a rationale to supplement with MCT oil to…
Why is an IV more hydrating than salted water? | Masterjohn Q&A Files #303
Short Answer: If it can’t be explained by the dose of salt, it may be that the salt is not being absorbed orally. Glucose, starch,…
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How to Increase or Decrease SHBG? | Masterjohn Q&A Files #302
Short Answer: SHBG is increased by adiponectin (vitamin K2, insulin sensitivity), thyroid hormone, fasting physiology (AMPK, fat oxidation), and estrogen (especially estrone), while it is…
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Protein and Longevity | Masterjohn Q&A Files #301
Short Answer: While protein restriction may have value in people with established cancer or kidney disease, cycling robustly between fasting and feeding states is…
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Why do my urinary B6 markers say I'm deficient if I'm supplementing and my plasma levels are high-normal? | Masterjohn Q&A Files #300
Short answer: Low or low-normal alkaline phosphatase may raise the plasma B6 level over the cellular level. Tryptophan metabolites in urine reflect the B6 requirement…
The 3 Phases of Fasting: And How to Get Kicked Out of Each One | Masterjohn Q&A Files #299
Short answer: 4-6 hours after a meal the small intestine is emptied and the insulin-to-glucagon ratio declines; 25 hours after, hepatic glycogen is emptied; 5…
Will reishi, turmeric, or curcumin tank my testosterone? Masterjohn Q&A Files #298
Short answer: Probably not. Animal studies showing a difference use huge doses in an unrealistic context. Human studies show they don’t at doses used. Human…
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What if my A1C says I'm diabetic but my CGM says I'm fine? | Masterjohn Q&A Files #297
Short answer: Trust the CGM. HbA1c is confounded by red blood cell turnover and fructosamine 3-kinase activity. This episode was cut from the original Q&A…
Balancing Vitamin C and Glutathione: Final Report
Maintaining good GSH status is always important to protect high-dose C from generating oxalate and may often be important for preventing it from acting…
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Chips! The Only Ones I'll Endorse
MASA chips launch today. Traditionally nixtamalized organic corn fried in grass-fed beef tallow. Full-bodied and perfectly salty. My friend Steve, who is the one…
Recording and Transcript of the July 13, 2022 AMA
Glycine problems, deficiency signs when lab tests are normal, the 3 phases of fasting & what kicks you out, lipoic acid & methylation, sulfur…
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Lipoic Acid Saps Methyl Groups
At what dose should we be concerned, and what can we do about it? Yesterday, I held a live Q&A with Masterpass members, and one of…
Ancestral Health vs. Antagonistic Pleiotropy?
Why Nick Hiebert is wrong in using antagonistic pleiotropy to refute the ancestral health framework. I recently had a debate on Twitter Spaces with…
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Recording and Transcript of the June 16, 2022 AMA
SIBO; CGM/HbA1c conflicts; vitamin C, copper, and histamine; reishi, curcumin, and testosterone; magnesium problems; vitamin toxicity; fat malabsorption; tinnitus; baking glycine; much more. Time…
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A New Paradigm for Severe COVID
Arginine depletion and T cell suppression in severe COVID may be the rapid onset of a somewhat cancer-reminiscent state where vitamins A and D…
What I'm Doing for Allergies
Here's my experience. My protocol seems to be working so far! Read it here.
Can COVID Vaccines Exacerbate Seasonal Allergies?
A convenience Twitter poll raises the question; I've heard anecdotal support; the mechanism is obvious. Read it here.
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Balancing Vitamin C and Glutathione: Preliminary Report
Beyond a certain dose, vitamin C can begin taxing glutathione and rendering excess nitric oxide toxic. Here's how to prevent that. Read it here.
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Reversing Fatty Liver: How Long Does It Take? | Masterjohn Q&A Files #296
Short answer: You should be able to see changes on imaging within a few weeks if your approach is working well, but ultimately this is…
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What's the difference between 25(OH)D and 1,25(OH)2D when it comes to the VDR? | Masterjohn Q&A Files #295
Short answer: 25(OH)D is 1000 times weaker at activating the VDR than 1,25(OH)D, but 1000 times more abundant. This is why I advocate measuring both,…
Protecting Against Spike Protein Toxicity With Sulfur, Selenium, and Sunlight
Spike Protein Toxicity Part 2: Creating resilience with thioredoxin, glutathione, selenium, riboflavin, NADPH, and sunlight. Read it here.
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The Emerging Food Crisis
My tentative view on what is causing it and what to do about it. This is NOT caused primarily by the conflict in Ukraine…
The Spike Protein As a Pore-Forming Toxin
The spike protein pokes holes in cell membranes at concentrations much lower than those achieved with vaccination, contributing to COVID-like illness and mitochondrial damage.…
Can the Vaccines Write the Spike Protein Into the Human Genome?
Limitations to the Feb 25 paper on reverse transcription notwithstanding, something has to be radically extending the half-life well beyond anything that could be…
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A Brand New Study on PCR-Negative COVID-Like Illness Suggests It is Often… COVID!
If PCR-negative COVID-like illness is often COVID, every single test-negative case control study is completely worthless and the vaccine trial efficacy numbers mean nothing…
Continue Reading A Brand New Study on PCR-Negative COVID-Like Illness Suggests It is Often… COVID!
COVID Vaccines Impair Response to Variants of Concern
The new paper showing the spike protein is found in armpit lymph nodes at least 60 days after vaccination also shows that immune imprinting…
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Explaining the “Hospitalization Paradox”
How a negative PCR test can serve as a marker for systemic inflammation and spike protein toxicity, creating a widely exploited statistical anomaly to…
Test-Negative Case Control Studies Are a Scam
Test-negative case control studies are abundant in the era of COVID, and are the primary type of observational study used to calculate vaccine efficacy.…
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Releasing Iron in Long-COVID: Copper, Fasting, and Cooling Inflammation
Last week I published two articles on iron, one suggesting it could play a role in post-COVID fatigue and hair loss, and the second…
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The Pandemic of PCR-Negative COVID-Like Illness
Disclaimer: I am not a medical doctor and this is not medical advice. My goal is to empower you with information. I will not…
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Could the COVID Vaccines Mess With Iron Metabolism?
Disclaimer: I am not a medical doctor and this is not medical advice. My goal is to empower you with information. I will not…
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Iron for Post-COVID Hair Loss and Fatigue
Disclaimer: I am not a medical doctor and this is not medical advice. I have a PhD in Nutritional Sciences, and this post is educational…
Strategizing Against Vaccine Mandates with Angela McArdle
In this episode, Chris Masterjohn interviews Angela McArdle on strategies to defeat the mandates. McArdle is the current chair of the Los Angeles Libertarian…
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Dmitry Kats, PhD: From Niatonin to Niacur
In this episode, I have Dr. Dmitry Kats, MPH, PhD. He has a PhD in epidemiology from the University of North Carolina at Chapel…
The Best of 2021
As we look forward with hope and determination toward a wonderful 2022, let us first briefly look back on the best of 2021. Here…
How to Fix a Sore Throat
Something is going around — perhaps in many cases a mild case of omicron — that is leaving people with isolated sore throats, and…
Jessica Rose: VAERS, Myocarditis, COVID Vaccines, and So Much More
In this episode, I have a fascinating 3-hour conversation with Dr. Jessica Rose about all things related to COVID vaccines, ranging from interpreting the…
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Patenting the Human Genome With Jorge Contreras
In this episode, I interview Law Professor Jorge Contreras about the past, present, and future of biotech companies patenting the human genome. Jorge L.…
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Tess Lawrie: Ivermectin, COVID Vaccines, and More
In this episode, I interview Tess Lawrie about ivermectin, public health corruption, and COVID vaccines. Tess is a medical doctor with expertise in research…
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Stephanie Seneff
In this episode, I interview Stephanie Seneff, PhD, on her hypothesis about glyphosate, deuterium, and COVID. This is a brilliant hypothesis that suggests that…
Uncensored: Coming Soon
This post is not ready yet, but will cover methods of censorship-resilience I am working on.
Fauci, Gates, and the Biosecurity State As Told by RFK Jr.
A review of The Real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health (2021) by Robert F. Kennedy,…
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Dr. David Brownstein
YouTube Audio In this interview with Dr. David Brownstein, best known for his use of iodine and nebulized hydrogen peroxide, we discuss his treatment…
Did the Pfizer Trial Show the Vaccine Increases Heart Disease Deaths?
Disclaimer: I am not a medical doctor and this is not medical advice. My goal is to empower you with information. I will not…
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COVID Vaccines: In Search of All-Cause Mortality
Disclaimer: I am not a medical doctor and this is not medical advice. My goal is to empower you with information. I will not…
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Black Friday Roundup and Masterpass Upgrade
Happy Thanksgiving! I am extremely grateful to you for supporting my work in whatever way you have and for being part of our community.…
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My Speech (and Full Footage!) at the Nov 20th NYC World Wide Rally for Freedom
The World Wide Rally for Freedom is a globally organized protest against vaccine mandates and more broadly for these five freedoms: freedom of speech…
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How I Lost my “COVID Weight”
Unlike Drew Manning, I didn't gain weight in 2020 on purpose. I gained it because I am incredibly vulnerable to stress-induced weight gain and…
Safe and Effective, But Based on Lies
This will be shocking to anyone who assumed “safe and effective” may have been based on truth. Read the scathing British Medical Journal exposé here.
New CDC Natural Immunity Study Uncensored Slide Deck
Please share these slides everywhere! On a computer, you can left click (control click on a Mac) and choose “save image,” and on a…
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The New CDC Study on Natural Immunity
Disclaimer: I am not a medical doctor and this is not medical advice. My goal is to empower you with information. I will not…
Do Americans Have the Right to Eat Healthy Food?
Review published July 31, 2013 There is no absolute right to consume or feed children any particular food. . . . There is no…
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Natural Immunity Uncensored Slide Deck
Please share these slides everywhere! On a computer, you can left click (control click on a Mac) and choose “save image,” and on a…
Natural Immunity Vs. Vaccination
Disclaimer: I am not a medical doctor and this is not medical advice. My goal is to empower you with information. I will not…
Post-COVID Labwork
Disclaimer: I am not a medical doctor and this is not medical advice. I have a PhD in Nutritional Sciences, and this post is educational…
The Real Reason for Vaccine Passports
Tracking vaccine status is an entrypoint for tracking everything you do, say, and believe as a means of controlling your access to everything right…
Omega-3 Fatty Acids and COVID
Disclaimer: I am not a medical doctor and this is not medical advice. I have a PhD in Nutritional Sciences, and analyzing research on…
If glutathione whitens your skin, is that good or bad? | Masterjohn Q&A Files #294
Short Answer: Measure this against whether it increases your likelihood of burning. If it does, it’s probably a bad thing, but if it doesn’t,…
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Vitamin D supplements, testing, and interactions with the vaccine. | Masterjohn Q&A Files #293
Short Answer: Vaccination shouldn’t change the vitamin D requirement. Quarterly testing makes sense for someone who has never tested before or who wants to…
BH4 vs tyrosine for low neurotransmitters and a high phenylalanine-to-tyrosine ratio. | Masterjohn Q&A Files #292
Short Answer: BH4 is expensive and requires very high doses, so if the problem is modest it can much more easily be solved by…
Does TMG have to be taken in the fasting state? | Masterjohn Q&A Files #291
Short Answer: While the body will tend to use TMG for methylation in the fasting state, it is normally found in food, so you…
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The One Amino Acid That Could Cure COVID
Disclaimer: I am not a medical doctor and this is not medical advice. I have a PhD in Nutritional Sciences and this information is educational…
Is urinary mycotoxin testing useful for indoor mold exposure? | Masterjohn Q&A Files #290
Short Answer: When I had a serious case of indoor mold-induced illness, I tested my urine and my apartment dust for mycotoxins. Both were…
Ferritin sky-high without hemochromatosis? | Masterjohn Q&A Files #289
Short Answer: Even if genetics and other bloodwork don’t look like hemochromatosis, sky-high ferritin justifies trying to lower it with blood donation or phlebotomy…
Continue Reading Ferritin sky-high without hemochromatosis? | Masterjohn Q&A Files #289
Will the booster shot be worth it? | Masterjohn Q&A Files #288
Short Answer: If optimizing for efficacy, the booster shot will likely be worth it for Pfizer, whereas other vaccines don’t have clear evidence of…
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How to use carbs and glycine for sleep. | Masterjohn Q&A Files #287
Short Answer: To get adequate raw material for melatonin synthesis in the brain, carbs can come any time of day and are best if…
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What are the downsides to taking prescription calcitriol for bones? | Masterjohn Q&A Files #286
Short Answer: It requires more frequent dosing and has some risk of hypercalcemia, and it would be best to make sure you have adequate…
Version 7 of the COVID Guide is Now Out!
Newly updated September 25, 2021, and now in Version 7: The Food and Supplement Guide for the Coronavirus Version 7 This guide provides my…
Does quinolinate sometimes indicate niacin or inflammation instead of B6? | Masterjohn Q&A Files #285
Short Answer: B6 cannot be ruled out, though inflammation and estrogen could also be involved. While it is possibly a regulated means of increasing…
Why would 5,000 IU vitamin D cause tooth sensitivity? | Masterjohn Q&A Files #284
Short Answer: While it is unclear, it could relate to vitamin K depletion, hypercalcemia, or compensation in acid-base balance. First and foremost, use the…
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What’s the best and most affordable diet for a hungry teenage boy? | Masterjohn Q&A Files #283
Short Answer: A half a gram to a gram of protein per pound of bodyweight, no more than 20-40 grams of that from protein…