Showing: 7 - 12 of 293 Articles

How to use carbs and glycine for sleep. | Masterjohn Q&A Files #287

Short Answer: To get adequate raw material for melatonin synthesis in the brain, carbs can come any time of day and are best if high-glycemic. To suppress brain histamine levels, carbs in the evening, with low protein and relatively low fat, is best. From among protein, collagen is best at night for the glycine. Watch …

What are the downsides to taking prescription calcitriol for bones? | Masterjohn Q&A Files #286

Short Answer: It requires more frequent dosing and has some risk of hypercalcemia, and it would be best to make sure you have adequate D and magnesium and aren’t overdoing anything that could deplete D, such as other fat-soluble vitamins, first. Watch the video or listen to the podcast with the links below. You can …

Does quinolinate sometimes indicate niacin or inflammation instead of B6? | Masterjohn Q&A Files #285

Short Answer: B6 cannot be ruled out, though inflammation and estrogen could also be involved. While it is possibly a regulated means of increasing excitatory effects of quinolinate, it makes sense to assume it may respond to B6. Watch the video or listen to the podcast with the links below. You can obtain a full …

Why would 5,000 IU vitamin D cause tooth sensitivity? | Masterjohn Q&A Files #284

Short Answer: While it is unclear, it could relate to vitamin K depletion, hypercalcemia, or compensation in acid-base balance. First and foremost, use the full testing algorithm in Testing Nutritional Status: The Ultimate Cheat Sheet (available at https://chrismasterjohnphd.com/cheatsheet) rather than just testing 25(OH)D to determine deficiency. Watch the video or listen to the podcast with …

What’s the best and most affordable diet for a hungry teenage boy? | Masterjohn Q&A Files #283

Short Answer: A half a gram to a gram of protein per pound of bodyweight, no more than 20-40 grams of that from protein powder, and whole foods supplying the targets for vitamins and minerals, erring on the side of overshooting them. Lentils and other legumes as primary carb foods and supply a portion of …

Why would MCV be elevated if MMA and FIGlu are normal? | Masterjohn Q&A Files #282

Short Answer: If the cause is nutritional, FIGlu cannot rule out folate deficiency as a cause because it reflects tetrahydrofolate rather than methylene-THF. So, increasing the dose of folate or switching from methylfolate to folinic acid could be tried. Otherwise the most likely  nutritional solution would be copper. Watch the video or listen to the …